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Research Associate / Senior Research Associate, Preclinical Research

Company: Bevov
Location: Kent
Posted on: September 9, 2021

Job Description:

Job Description

Our client is a biotechnology company leading a new generation of gene therapy.  With our proprietary redosable ceDNA technology, we are expanding the reach of gene therapy.  Our client goal is to bring the life-saving benefits of gene therapy to more people, living with a broader range of diseases, in more places around the world and vision, is to make the ravages of genetic disease as imaginary to the next generation as polio feels to children today. 

Our client is a thriving, collaborative, creative community of diverse talents, beliefs, and experiences relentlessly dedicated to our mission. Founded and launched by Atlas Venture. Headquartered in Cambridge, Massachusetts. Committed to a future where more people can live full lives.

The client is looking for a collaborative, versatile, and highly motivated Senior Associate Scientist/ Scientist to join our Preclinical Research group. For this lab-based position, the successful candidate will be responsible for developing and implementing assays to support disease biology and advance our non-viral gene therapy platform, contributing to our liver disease programs from lead optimization to candidate selection.

Responsibilities

  • Develop and execute assays to assess protein expression and distribution (e.g. immunofluorescence, Western blot, flow cytometry, qPCR) or biological effects (e.g. localization, enzyme activity, signaling pathway activation/inhibition), from tissue samples, plasma/serum, and cell culture lysates.
  • Conduct in vitro experiments including cell model characterization, transfection, and end point assays.
  • Design and troubleshoot experiments, analyze data, and interpret results.
  • Interface with CROs for specific study areas to coordinate research activities.
  • Document experiments and summarize studies in written reports and oral presentations.

Qualifications

  • Bachelor’s (Master’s degree preferred) in a related scientific field (e.g. Biology, Biochemistry, Molecular and Cell Biology).
  • Minimum of 3-years of relevant laboratory experience.
  • Excellent lab skills and the ability to work independently to conduct and troubleshoot experiments, as well as analyze, interpret, and present data.
  • Proficient in protein detection methods including immunostaining, western blot, and enzymatic assays from in vivo (tissue/plasma/serum) or in vitro (cell culture) samples.
  • Familiarity with cell culture manipulation techniques (e.g., transfections, cell-based assays).
  • Experience with cell and tissue staining (IF, IHC, ICC) and imaging /analysis methods a plus (confocal microscopy, flow cytometry).
  • Ability to multi-task to support multiple projects and work in a matrixed environment.
  • Prior experience with gene therapy and/or lead optimization a plus.

Benefits

Our client is in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, gender, religion, national origin, gender identity, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Our client will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Keywords: Bevov, Kent , Research Associate / Senior Research Associate, Preclinical Research, Other , Kent, Washington

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